ClueGO Python Client & Pathway Enrichment Analysis

Overview

This project has two primary goals:

1. Pathway Enrichment Analysis – I am using Cytoscape + ClueGO to identify enriched biological pathways from gene lists. The objective of the analysis is to identify the pathways affected by curcumin treated cells
2. ClueGO Python Client – I am writing a Python interface to the ClueGO[1] app to make it easier to automate analysis with the ClueGO REST API.

[1] Bindea G, Mlecnik B, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman WH, Pagès F, Trajanoski Z, Galon J. ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics. 2009 Apr 15;25(8):1091-3. doi: 10.1093/bioinformatics/btp101. Epub 2009 Feb 23. PMID: 19237447; PMCID: PMC2666812.