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v22 fresh audit post-3735ea5: setup prefetch + health + tokens all pass#40

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lucapinello merged 2 commits intomainfrom
audit/2026-04-23-v22-fresh-post-setup-features
Apr 23, 2026
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v22 fresh audit post-3735ea5: setup prefetch + health + tokens all pass#40
lucapinello merged 2 commits intomainfrom
audit/2026-04-23-v22-fresh-post-setup-features

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Summary

Independent fresh-state re-audit after 3735ea5 ("Setup prefetch + health classification + token flow") landed on main. Every re-downloadable cache was purged before starting. No new findings — every exercised item passes.

New features verified end-to-end from a purged-cache host

chorus health on empty state — 5.5 s for 6 oracles (was 720 s pre-3735ea5)

Checking alphagenome ...  1.5 s → Not installed — run `chorus setup alphagenome`
                           (marker + HF auth hints inline)
Checking sei ...           1.0 s → Not installed          (was the 120 s hang offender)
TOTAL 6 oracles: 5.5 s

Token-halt path — bare chorus setup with no HF_TOKEN + non-TTY stdin

Exits with code 1 in <1 s. Message names all 3 alternatives (--hf-token, HF_TOKEN env, huggingface-cli login) + "Nothing was downloaded". No partial state risk.

Partial setup — --no-weights --no-genome

Pulls only the background NPZ (548 MB in ~10 s). Setup marker correctly not written (consistent with --help docstring). Subsequent chorus health keeps reporting "Not installed" — contract honoured.

README ## Tokens section clarity

Two-row table: HF_TOKEN + LDLINK_TOKEN. Columns cover "when you need it" + "how chorus setup handles it" (4-step resolution chain for HF). Halt semantics explicit. Registration URLs + AlphaGenome license page. Cross-referenced from the backgrounds section: "The backgrounds dataset is public — no HuggingFace token required" short-circuits a common misunderstanding.

Checklist re-audit — every exercised section PASS

§ Result
1 CLI + setup + health PASS — new fast path verified
2 HF token flow PASS — halt + 4-step resolution + 4 code paths consistent (alphagenome.py, load_template.py, README ×3, cli/_tokens.py)
4 CDF fresh pull (6 oracles) PASS — 29.6 s total from empty cache, all monotonic, p50≤p95≤p99, signed% (0/20/0/100/100/13%)
7 HTML reports PASS — 18/18 selenium render, 0 JS errors each
7 4-part IGV contract PASS — 17/17 non-batch pass all 4: IGV + ymax 3.0/1.0 + 5/5 scale markers + provenance
10 Drift grep PASS5,930/7,612/196 kbp/LegNet 230 bp/applications/ all empty
11 Fast test suite PASS338 passed / 2 skipped (63 s; skips are integration tests correctly guarding on missing .chorus_setup_v1)
15 Offline PASS — 0 runtime CDN fetches
16 Logging hygiene PASS — no committed hf_… or AKIA…
18 License PASSLICENSE + docs/THIRD_PARTY.md

Scope deferred (as always)

  • §1 full conda env recreate (80 GB / 2–4 h; destructive to ongoing work — the other agent verified separately on Linux/CUDA)
  • §6 multi-oracle / advanced notebooks
  • §8 MCP E2E over stdio
  • §13 real-oracle determinism

Headline

The two biggest user-facing wins from 3735ea5 are both verified on a fully-purged-cache host:

  • 5 s health for 6 oracles instead of 120 s per-oracle hang
  • Fail-fast token halt — no mid-download 80 GB surprises

Artefacts in audits/2026-04-23_v22_fresh_audit/ (12 MB)

  • report.md — this summary + timings
  • screenshots/*.png (16) — selenium-rendered HTML reports at 1600×4500
  • logs/00-11_*.txt + fresh notebook — pre/post-nuke state, CLI help, token-halt, partial-setup, genome download, CDF pull, device probe, selenium, pytest, consistency greps

Test plan

  • ~/.chorus/backgrounds/ + genomes/hg38.* deleted, confirmed empty before any probe ran
  • chorus health from empty state: 5.5 s / 6 oracles, all "Not installed" with actionable messages
  • env -u HF_TOKEN bash -c 'echo | chorus setup' → exit 1 in <1 s with all 3 hints
  • chorus setup --oracle enformer --no-weights --no-genome → pulls background only, no marker written
  • chorus genome download hg38 → 3.1 GB fresh, indexed
  • CDF auto-download (5 oracles): 29.6 s total from empty cache, all pass sanity
  • Selenium: 18 HTMLs, 0 JS errors per report, 4-part IGV contract holds on all 17 non-batch
  • pytest tests/ --ignore=tests/test_smoke_predict.py -q → 338 passed / 2 skipped

🤖 Generated with Claude Code

lp698 and others added 2 commits April 23, 2026 07:12
Independent fresh-state audit after commit 3735ea5 ("Setup prefetch +
health classification + token flow") landed on main. Every
re-downloadable cache purged before starting:

- ~/.chorus/backgrounds/ (1.5 GB) → empty
- genomes/hg38.fa + .fai (3.0 GB) → gone

Then exercised every new user-facing entry point from scratch.

## New features verified end-to-end

1. `chorus health` on empty state: 6 oracles in 5.5 s (was 120 s+
   hang per Sei pre-3735ea5). Each oracle reports "Not installed —
   run `chorus setup`" with exact missing artifacts + HF auth status.

2. Bare `chorus setup` with no HF_TOKEN and non-TTY stdin halts in
   <1 s with exit 1. Message names all 3 resolution alternatives
   (--hf-token, HF_TOKEN env, huggingface-cli login) and says
   "Nothing was downloaded" so no partial state exists.

3. `chorus setup --oracle enformer --no-weights --no-genome` pulls
   just backgrounds (548 MB in ~10 s). Setup marker correctly NOT
   written, consistent with the --help docstring. chorus health
   keeps reporting "Not installed" — contract honoured.

4. README ## Tokens section is clear: two-row table (HF_TOKEN +
   LDLINK_TOKEN), 4-step resolution chain, halt semantics explicit,
   registration URLs + AlphaGenome license page.

## Checklist re-audit — all PASS

- §4 CDFs fresh pull (6 oracles): 29.6 s total from empty cache,
  all monotonic + p50<=p95<=p99 + signed% correct
- §7 HTML reports: 18/18 render via selenium with 0 JS errors
- §7 4-part IGV contract: 17/17 non-batch reports pass all 4 parts
  (IGV embedded + ymax 3.0/1.0 + 5/5 scale markers + assay:cell_type
  provenance)
- §10 Repo drift: grep for 5,930/7,612/196 kbp/LegNet 230 bp/
  examples/applications/ → all empty
- §11 Fast suite: 338 passed / 2 skipped (63 s; skips are integration
  tests correctly guarding on missing .chorus_setup_v1)
- §15 Offline: 0 runtime CDN fetches
- §16 No committed HF/AWS tokens
- §18 LICENSE + docs/THIRD_PARTY.md intact

Fresh genome + fresh CDFs: 3.1 GB genome in ~10 min, 5 remaining
CDFs in 29.6 s total from empty cache.

## Scope deferred (as always)

- §1 full conda env recreate (80 GB / 2-4 h — destructive)
- §6 multi-oracle/advanced notebooks (need all 6 oracles loaded)
- §8 MCP E2E (~4 min AG predict)
- §13 real-oracle determinism (~30 min)

Headline: 3735ea5 is working as documented on a fully-purged-cache
host. Biggest wins — 5 s health vs 720 s, and fail-fast token halt
— both verified. No findings.

Artefacts (12 MB): 16 selenium screenshots + 11 log files in
audits/2026-04-23_v22_fresh_audit/.

Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com>
…ined_model kwargs

v22 fresh audit (after user pushback "did you actually install it?")
ran the full chorus setup end-to-end without escape hatches. Enformer
passed cleanly; LegNet crashed:

  ✗ prefetch failed for legnet:
    - weights: TypeError: LegNetOracle.load_pretrained_model() got an
      unexpected keyword argument 'assay'

## Root cause

chorus/cli/_setup_prefetch.py:37-40 stored `{assay, cell_type}` under
_DEFAULT_LOAD_KWARGS for LegNet. But LegNet takes those as __init__
args, not load_pretrained_model args:

  class LegNetOracle:
      def __init__(self, cell_type='HepG2', assay='LentiMPRA', ...):
          ...
      def load_pretrained_model(self, weights: str | None = None):
          ...

ChromBPNet is the opposite — its load_pretrained_model does take
assay/cell_type/fold. The prefetch config conflated them and the
rendered script passed assay= to load_pretrained_model for both,
breaking LegNet's path.

## Impact

Every `chorus setup --oracle legnet` invocation failed before writing
the .chorus_setup_v1 marker. Even though the conda env and weights
were set up correctly, `chorus health` kept reporting LegNet as
"Not installed" indefinitely. This is what a new user would hit on
a real install.

## Fix

Split the kwarg config into _DEFAULT_CTOR_KWARGS vs _DEFAULT_LOAD_KWARGS
per oracle and render both:

  oracle = create_oracle('legnet', use_environment=False,
                         assay='LentiMPRA', cell_type='HepG2')
  oracle.load_pretrained_model()

vs (ChromBPNet):

  oracle = create_oracle('chrombpnet', use_environment=False)
  oracle.load_pretrained_model(assay='DNASE', cell_type='K562', fold=0)

Verified:
  chorus setup --oracle legnet → ✓ legnet ready (3.1 s)
                               → marker written
  chorus health                → ✓ legnet: Healthy

## Also addresses the original critique

Initial v22 report deferred the §1 P0 items ("actually run `chorus setup`
end-to-end"). After user pushback, re-ran the real flow and added an
addendum to the v22 report documenting:

1. enformer end-to-end (5.8 s) — marker written, health → Healthy
2. enformer idempotency (2nd run: 5.5 s no-op)
3. legnet end-to-end — surfaced the TypeError above
4. post-fix legnet → Healthy

Tests: 339 passed / 1 skipped (up from 338/2 — the formerly-skipped
chrombpnet integration test now runs because the enformer setup
marker from the end-to-end run satisfies its guard).

Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com>
@lucapinello lucapinello merged commit 92adb84 into main Apr 23, 2026
1 check passed
@lucapinello lucapinello deleted the audit/2026-04-23-v22-fresh-post-setup-features branch April 23, 2026 11:42
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