Thank you for developing CRISPResso2. It has made analysis of genome-editing NGS data much more straightforward and accessible for our work.
I have a more customized question and would greatly appreciate your guidance. As I understand it, CRISPResso2 evaluates each read and classifies edited reads as “modified reads.” In addition to the summary metrics, I would like to obtain per-read editing information—specifically, the read ID for each read and its corresponding editing status (e.g., unmodified vs modified, and ideally the type/position of the edit).
Could you please advise whether CRISPResso2 currently provides a way to export such per-read annotations? If not, I am happy to modify the code. In that case, could you point me to the relevant script/module(s) in the CRISPResso2 codebase where per-read classification is performed, so I can implement an export of read IDs and editing calls?
Thank you very much for your time and help.
Thank you for developing CRISPResso2. It has made analysis of genome-editing NGS data much more straightforward and accessible for our work.
I have a more customized question and would greatly appreciate your guidance. As I understand it, CRISPResso2 evaluates each read and classifies edited reads as “modified reads.” In addition to the summary metrics, I would like to obtain per-read editing information—specifically, the read ID for each read and its corresponding editing status (e.g., unmodified vs modified, and ideally the type/position of the edit).
Could you please advise whether CRISPResso2 currently provides a way to export such per-read annotations? If not, I am happy to modify the code. In that case, could you point me to the relevant script/module(s) in the CRISPResso2 codebase where per-read classification is performed, so I can implement an export of read IDs and editing calls?
Thank you very much for your time and help.