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    <title>Blachly Lab</title>
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    <description>Recent content on Blachly Lab</description>
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    <copyright>&amp;copy; Blachly Lab, 2022</copyright>
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    <item>
      <title>Apo ngankeu</title>
      <link>https://blachlylab.github.io/alumni/alumni1/</link>
      <pubDate>Thu, 21 Jul 2022 15:52:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/alumni/alumni1/</guid>
      <description>I am an experienced scientist with a demonstrated history of working in Biomedical Research. Skilled in Biochemistry, Molecular Biology, Biotechnology, Cell Culture, Genomic Research. Experienced in nucleic acid research, gained through several years of management of next-generation sequencing experiments, projects working with micro-RNA and non-coding RNA in cancer, and forging the use of new NGS experimental techniques to explore the genetic and epigenetic mosaicism in leukemia. Professional development in Clinical Pharmacology and Applied Clinical and Pre-clinical Research, focused in the development of safe, novel, therapeutic tools, in accordance with the Good Laboratory Practices and Good Clinical Practice guidelines.</description>
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    <item>
      <title>HOXD13 alterations in synpolydactyly</title>
      <link>https://blachlylab.github.io/publication/humu.24304/</link>
      <pubDate>Fri, 12 Nov 2021 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/humu.24304/</guid>
      <description></description>
    </item>
    
    <item>
      <title>VIP152 Is a Novel CDK9 Inhibitor with Efficacy in Chronic Lymphocytic Leukemia</title>
      <link>https://blachlylab.github.io/publication/blood-2021-153812/</link>
      <pubDate>Fri, 12 Nov 2021 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2021-153812/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Molecular classification of a complex structural rearrangement of the RB1 locus</title>
      <link>https://blachlylab.github.io/publication/40478-021-01164-z/</link>
      <pubDate>Mon, 12 Apr 2021 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/40478-021-01164-z/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia</title>
      <link>https://blachlylab.github.io/publication/s41467-021-26400-x/</link>
      <pubDate>Fri, 12 Mar 2021 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s41467-021-26400-x/</guid>
      <description></description>
    </item>
    
    <item>
      <title>A phase I study of lenalidomide plus chemotherapy with idarubicin and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high‐risk myelodysplastic syndrome</title>
      <link>https://blachlylab.github.io/publication/ajh.25958/</link>
      <pubDate>Sat, 12 Dec 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/ajh.25958/</guid>
      <description></description>
    </item>
    
    <item>
      <title>TP-0903 is active in models of drug-resistant acute myeloid leukemia</title>
      <link>https://blachlylab.github.io/publication/jci-insight-140169/</link>
      <pubDate>Sat, 12 Dec 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/jci-insight-140169/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A</title>
      <link>https://blachlylab.github.io/publication/s41375-020-0872-3/</link>
      <pubDate>Mon, 12 Oct 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s41375-020-0872-3/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Entospletinib in Combination with Induction Chemotherapy in Previously Untreated Acute Myeloid Leukemia: Response and Predictive Significance of HOXA9 and MEIS1 Expression</title>
      <link>https://blachlylab.github.io/publication/1078-0432.ccr-20-1064/</link>
      <pubDate>Wed, 12 Aug 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/1078-0432.ccr-20-1064/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A</title>
      <link>https://blachlylab.github.io/publication/pnas.2014732117/</link>
      <pubDate>Wed, 12 Aug 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/pnas.2014732117/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Large-Scale Drug Screen Identifies FDA-Approved Drugs for Repurposing in Sickle-Cell Disease</title>
      <link>https://blachlylab.github.io/publication/jcm9072276/</link>
      <pubDate>Sun, 12 Jul 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/jcm9072276/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia</title>
      <link>https://blachlylab.github.io/publication/cancers12061574/</link>
      <pubDate>Fri, 12 Jun 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/cancers12061574/</guid>
      <description></description>
    </item>
    
    <item>
      <title>LC-FACSeq is a method for detecting rare clones in leukemia</title>
      <link>https://blachlylab.github.io/publication/jci-insight-134973/</link>
      <pubDate>Fri, 12 Jun 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/jci-insight-134973/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Novel BCL2 mutations in venetoclax-resistant, ibrutinib-resistant CLL patients with BTK/PLCG2 mutations</title>
      <link>https://blachlylab.github.io/publication/blood-2019003722/</link>
      <pubDate>Thu, 12 Mar 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2019003722/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Novel BCL2 mutations in venetoclax-resistant, ibrutinib-resistant CLL patients with BTK/PLCG2 mutations</title>
      <link>https://blachlylab.github.io/publication/blood.2019003722/</link>
      <pubDate>Thu, 12 Mar 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood.2019003722/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Quantifying Hematopoietic Stem Cell Clonal Diversity by Selecting Informative Amplicon Barcodes</title>
      <link>https://blachlylab.github.io/publication/s41598-020-59119-8/</link>
      <pubDate>Wed, 12 Feb 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s41598-020-59119-8/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Transcriptionally Active Androgen Receptor Splice Variants Promote Hepatocellular Carcinoma Progression</title>
      <link>https://blachlylab.github.io/publication/0008-5472.can-19-1117/</link>
      <pubDate>Wed, 12 Feb 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/0008-5472.can-19-1117/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Characterization and mitigation of fragmentation enzyme-induced dual stranded artifacts</title>
      <link>https://blachlylab.github.io/publication/lqaa070/</link>
      <pubDate>Sun, 12 Jan 2020 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/lqaa070/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Enumerating Functional HSC Clones in the Zebrafish Using Gestalt</title>
      <link>https://blachlylab.github.io/publication/blood-2019-131503/</link>
      <pubDate>Tue, 12 Nov 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2019-131503/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia</title>
      <link>https://blachlylab.github.io/publication/1078-0432.ccr-19-0725/</link>
      <pubDate>Tue, 12 Nov 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/1078-0432.ccr-19-0725/</guid>
      <description></description>
    </item>
    
    <item>
      <title>LC-Facseq: A Novel Method for Detecting Rare Resistant Clones in Leukemia</title>
      <link>https://blachlylab.github.io/publication/blood-2019-126070/</link>
      <pubDate>Tue, 12 Nov 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2019-126070/</guid>
      <description></description>
    </item>
    
    <item>
      <title>NPM1 mutations Using Deep Amplicon Sequencing and Broad Next Generation Sequencing at the Time of Complete Remission Is Informative to Predicting Risk of Relapse Following Intensive Chemotherapy</title>
      <link>https://blachlylab.github.io/publication/blood-2019-130856/</link>
      <pubDate>Tue, 12 Nov 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2019-130856/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Rapid Molecular Diagnostics for Acute Myeloid Leukemia Using Single-Molecule Sequencing</title>
      <link>https://blachlylab.github.io/publication/blood-2019-131366/</link>
      <pubDate>Tue, 12 Nov 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2019-131366/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia</title>
      <link>https://blachlylab.github.io/publication/2159-8290.cd-19-0209/</link>
      <pubDate>Tue, 12 Nov 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/2159-8290.cd-19-0209/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Dr. Blachly Discusses ctDNA as a Biomarker in Hairy Cell Leukemia</title>
      <link>https://blachlylab.github.io/post/ctdna-as-a-biomarker-in-hairy-cell-leukemia/</link>
      <pubDate>Tue, 29 Oct 2019 16:50:58 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/post/ctdna-as-a-biomarker-in-hairy-cell-leukemia/</guid>
      <description>James Blachly, MD, assistant professor of Internal Medicine and Biomedical Informatics at the Ohio State Comprehensive Cancer Center, discusses the role of circulating tumor DNA (ctDNA) as a biomarker for patients with hairy cell leukemia.
Blachly says ctDNA is an important emerging biomarker in many different cancer types, as well as non-cancer applications. However, this has not been tested previously in hairy cell leukemia. This disease behaves like any other non-Hodgkin lymphoma and sheds a moderate amount of cell free DNA that is readily detectable.</description>
    </item>
    
    <item>
      <title>Why I Chose a Career in Hematology</title>
      <link>https://blachlylab.github.io/post/why-i-chose-a-career-in-hematology/</link>
      <pubDate>Mon, 23 Sep 2019 16:50:58 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/post/why-i-chose-a-career-in-hematology/</guid>
      <description>Dr. James Blachly, a hematologist at the OSUCCC – James, chose a career in hematology because of the fast-paced environment surrounding leukemia as well as personal ties to the disease.</description>
    </item>
    
    <item>
      <title>Clinical and molecular characterization of patients with acute myeloid leukemia and sole trisomies of chromosomes 4, 8, 11, 13 or 21</title>
      <link>https://blachlylab.github.io/publication/s41375-019-0560-3/</link>
      <pubDate>Mon, 12 Aug 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s41375-019-0560-3/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia</title>
      <link>https://blachlylab.github.io/publication/blood.2019000490/</link>
      <pubDate>Mon, 12 Aug 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood.2019000490/</guid>
      <description></description>
    </item>
    
    <item>
      <title>BRCA1/2 Functional Loss Defines a Targetable Subset in Leiomyosarcoma</title>
      <link>https://blachlylab.github.io/publication/theoncologist.2018-0448/</link>
      <pubDate>Fri, 12 Jul 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/theoncologist.2018-0448/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Preclinical activity and a pilot phase I study of pacritinib, an oral JAK2/FLT3 inhibitor, and chemotherapy in FLT3-ITD-positive AML</title>
      <link>https://blachlylab.github.io/publication/s10637-019-00786-4/</link>
      <pubDate>Sun, 12 May 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s10637-019-00786-4/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically</title>
      <link>https://blachlylab.github.io/publication/s41375-019-0390-3/</link>
      <pubDate>Tue, 12 Feb 2019 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s41375-019-0390-3/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL</title>
      <link>https://blachlylab.github.io/publication/nejmoa1812836/</link>
      <pubDate>Wed, 12 Dec 2018 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/nejmoa1812836/</guid>
      <description></description>
    </item>
    
    <item>
      <title>NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome</title>
      <link>https://blachlylab.github.io/publication/s41375-018-0147-4/</link>
      <pubDate>Wed, 12 Dec 2018 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s41375-018-0147-4/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT3-ITD AML</title>
      <link>https://blachlylab.github.io/publication/cts.12669/</link>
      <pubDate>Thu, 12 Jul 2018 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/cts.12669/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Genomic amplification of CDK4 in dedifferentiated liposarcomas as a predictive biomarker for microtubule disrupting agents.</title>
      <link>https://blachlylab.github.io/publication/jco.2018.36.15_suppl.11549/</link>
      <pubDate>Sat, 12 May 2018 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/jco.2018.36.15_suppl.11549/</guid>
      <description></description>
    </item>
    
    <item>
      <title>BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor</title>
      <link>https://blachlylab.github.io/publication/2159-8290.cd-17-0902/</link>
      <pubDate>Thu, 12 Apr 2018 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/2159-8290.cd-17-0902/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies</title>
      <link>https://blachlylab.github.io/publication/s41375-018-0068-2/</link>
      <pubDate>Mon, 12 Feb 2018 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/s41375-018-0068-2/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Landscape of Microsatellite Instability Across 39 Cancer Types</title>
      <link>https://blachlylab.github.io/publication/po.17.00073/</link>
      <pubDate>Tue, 12 Sep 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/po.17.00073/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma</title>
      <link>https://blachlylab.github.io/publication/pnas.1704371114/</link>
      <pubDate>Sat, 12 Aug 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/pnas.1704371114/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Near-tetraploidy is associated with Richter transformation in chronic lymphocytic leukemia patients receiving ibrutinib</title>
      <link>https://blachlylab.github.io/publication/bloodadvances.2017007302/</link>
      <pubDate>Sat, 12 Aug 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/bloodadvances.2017007302/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors</title>
      <link>https://blachlylab.github.io/publication/jmoldx-2017-05-006/</link>
      <pubDate>Sat, 12 Aug 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/jmoldx-2017-05-006/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Novel SF3B1 in-frame deletions result in aberrant RNA splicing in CLL patients</title>
      <link>https://blachlylab.github.io/publication/bloodadvances.2017007062/</link>
      <pubDate>Wed, 12 Jul 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/bloodadvances.2017007062/</guid>
      <description></description>
    </item>
    
    <item>
      <title>The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia</title>
      <link>https://blachlylab.github.io/publication/leu201786/</link>
      <pubDate>Fri, 12 May 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/leu201786/</guid>
      <description></description>
    </item>
    
    <item>
      <title>The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia</title>
      <link>https://blachlylab.github.io/publication/oncotarget.15401/</link>
      <pubDate>Sun, 12 Feb 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/oncotarget.15401/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality</title>
      <link>https://blachlylab.github.io/publication/0008-5472.can-16-1386/</link>
      <pubDate>Thu, 12 Jan 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/0008-5472.can-16-1386/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Performance evaluation for rapid detection of pan-cancer microsatellite instability with MANTIS</title>
      <link>https://blachlylab.github.io/publication/oncotarget.13918/</link>
      <pubDate>Thu, 12 Jan 2017 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/oncotarget.13918/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Interferon-γ Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells*</title>
      <link>https://blachlylab.github.io/publication/jbc.m116.753145/</link>
      <pubDate>Mon, 12 Dec 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/jbc.m116.753145/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Targeting BTK through microRNA in chronic lymphocytic leukemia</title>
      <link>https://blachlylab.github.io/publication/blood-2016-07-727750/</link>
      <pubDate>Mon, 12 Dec 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2016-07-727750/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia</title>
      <link>https://blachlylab.github.io/publication/leu.2016.332/</link>
      <pubDate>Sat, 12 Nov 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/leu.2016.332/</guid>
      <description></description>
    </item>
    
    <item>
      <title>MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair</title>
      <link>https://blachlylab.github.io/publication/humu.23036/</link>
      <pubDate>Wed, 12 Oct 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/humu.23036/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia</title>
      <link>https://blachlylab.github.io/publication/bjh.14254/</link>
      <pubDate>Fri, 12 Aug 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/bjh.14254/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2</title>
      <link>https://blachlylab.github.io/publication/leu2016196/</link>
      <pubDate>Tue, 12 Jul 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/leu2016196/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Blachly Lab Tools and Software</title>
      <link>https://blachlylab.github.io/project/tools/</link>
      <pubDate>Tue, 12 Jul 2016 16:10:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/project/tools/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Completed Research Projects</title>
      <link>https://blachlylab.github.io/project/finished/</link>
      <pubDate>Tue, 12 Jul 2016 16:10:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/project/finished/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Research Projects</title>
      <link>https://blachlylab.github.io/project/research/</link>
      <pubDate>Tue, 12 Jul 2016 16:10:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/project/research/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Esko Kautto</title>
      <link>https://blachlylab.github.io/member/member2/</link>
      <pubDate>Tue, 12 Jul 2016 15:52:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/member/member2/</guid>
      <description>Experienced Informatics Specialist with a demonstrated history of working in the hospital &amp;amp; health care industry. Skilled in Python, PHP, E-commerce, C++, and WordPress. Strong research professional with a Bachelor’s Degree focused in Computer Science and Engineering from The Ohio State University. In his PhD thesis work, Esko Kautto has crafted a same-day, broad, sequencing-based molecular diagnostic test for AML that will transform patient care.</description>
    </item>
    
    <item>
      <title>James Blachly</title>
      <link>https://blachlylab.github.io/member/member1/</link>
      <pubDate>Tue, 12 Jul 2016 15:52:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/member/member1/</guid>
      <description>Dr. Blachly is an oncologist focused on the treatment of patients diagnosed with hairy cell leukemia, acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL) and chronic lymphocytic leukemia (CLL). He’s a member of the Leukemia Research Program at the OSUCCC – James and serve as an assistant professor in The Ohio State University Division of Hematology. As a member of the Leukemia Research Program at the OSUCCC – James, his research interest is in genomics and gene transcription in leukemia and its relevance in experimental therapeutics.</description>
    </item>
    
    <item>
      <title>Kat Kananen</title>
      <link>https://blachlylab.github.io/member/member4/</link>
      <pubDate>Tue, 12 Jul 2016 15:52:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/member/member4/</guid>
      <description>Kathryn earned a B.S in bioinformatics and computational biology from Iowa State University and a Master’s of Applied Bioinformatics at Cranfield University, Cranfield, UK. She was an undergraduate researcher for four years working on analysis of genomics and population architecture of maize and teosinte developing expertise in genetics, bioinformatics, and field work. In 2016, she received the Iowa State Emerging Leadership Award and actively volunteered as a Speaker’s Bureau panelist and helped with event planning / fundraising, while completing her undergraduate.</description>
    </item>
    
    <item>
      <title>Thomas Gregory</title>
      <link>https://blachlylab.github.io/member/member3/</link>
      <pubDate>Tue, 12 Jul 2016 15:52:22 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/member/member3/</guid>
      <description>Thomas is a bioinformatician / computational biologist with 4 years of experience creating novel algorithms for the analysis of NGS data as well as the creation and maintenance of various NGS analysis pipelines. He currently have experience in various programming languages: python, R, D, Rust, Go, Java, and JavaScript; he has also worked on a variety of projects: development of a variant caller, AWS hosted real-time data analysis of NGS data, development of new analysis pipelines for novel laboratory protocols, transformation of VCF variant data into spreadsheets for clinical staff.</description>
    </item>
    
    <item>
      <title>Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifi es miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia</title>
      <link>https://blachlylab.github.io/publication/2159-8290.cd-16-0023/</link>
      <pubDate>Sun, 12 Jun 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/2159-8290.cd-16-0023/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Structural characterization of NRAS isoform 5</title>
      <link>https://blachlylab.github.io/publication/pro.2916/</link>
      <pubDate>Sat, 12 Mar 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/pro.2916/</guid>
      <description></description>
    </item>
    
    <item>
      <title>HDAC Inhibition Induces MicroRNA-182, which Targets RAD51 and Impairs HR Repair to Sensitize Cells to Sapacitabine in Acute Myelogenous Leukemia</title>
      <link>https://blachlylab.github.io/publication/1078-0432.ccr-15-1063/</link>
      <pubDate>Fri, 12 Feb 2016 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/1078-0432.ccr-15-1063/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Clinical features and gene- and microRNA-expression patterns in adult acute leukemia patients with t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3)</title>
      <link>https://blachlylab.github.io/publication/leu2015345/</link>
      <pubDate>Sat, 12 Dec 2015 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/leu2015345/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Cancer Driver Log (CanDL) Catalog of Potentially Actionable Cancer Mutations</title>
      <link>https://blachlylab.github.io/publication/jmoldx-2015-05-002/</link>
      <pubDate>Sat, 12 Sep 2015 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/jmoldx-2015-05-002/</guid>
      <description></description>
    </item>
    
    <item>
      <title>MuCor: mutation aggregation and correlation</title>
      <link>https://blachlylab.github.io/publication/btw028/</link>
      <pubDate>Sun, 12 Jul 2015 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/btw028/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in chronic lymphocytic leukemia</title>
      <link>https://blachlylab.github.io/publication/pnas.1503587112/</link>
      <pubDate>Sun, 12 Apr 2015 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/pnas.1503587112/</guid>
      <description></description>
    </item>
    
    <item>
      <title>PKC-b as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL</title>
      <link>https://blachlylab.github.io/publication/blood-2014-05-574830/</link>
      <pubDate>Tue, 12 Aug 2014 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/blood-2014-05-574830/</guid>
      <description></description>
    </item>
    
    <item>
      <title>PrEMeR-CG: inferring nucleotide level DNA methylation values from MethylCap-seq data</title>
      <link>https://blachlylab.github.io/publication/btu583/</link>
      <pubDate>Tue, 12 Aug 2014 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/btu583/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia</title>
      <link>https://blachlylab.github.io/publication/clpt.2014.93/</link>
      <pubDate>Sat, 12 Apr 2014 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/clpt.2014.93/</guid>
      <description></description>
    </item>
    
    <item>
      <title>Emerging Drug Profile: Cyclin-Dependent Kinase Inhibitors</title>
      <link>https://blachlylab.github.io/publication/10428194.2013.783911/</link>
      <pubDate>Sat, 12 Oct 2013 16:37:31 +0200</pubDate>
      
      <guid>https://blachlylab.github.io/publication/10428194.2013.783911/</guid>
      <description></description>
    </item>
    
    <item>
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      <title></title>
      <link>https://blachlylab.github.io/approach/</link>
      <pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate>
      
      <guid>https://blachlylab.github.io/approach/</guid>
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      <title></title>
      <link>https://blachlylab.github.io/vacancy/vacancy1/</link>
      <pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate>
      
      <guid>https://blachlylab.github.io/vacancy/vacancy1/</guid>
      <description>Screen reader users may encounter difficulty with this site. For assistance with applying, please contact hr-accessibleapplication@osu.edu . If you have questions while submitting an application, please review these frequently asked questions .
Current Employees and Students: If you are currently employed or enrolled as a student at The Ohio State University, please l og in to Workday to use the internal application process. Welcome to The Ohio State University&amp;rsquo;s career site.</description>
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